335 research outputs found

    Language and Indigenous Health in Latin America: Case study of Mexico

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    Health disparities among indigenous and non-indigenous peoples serve as a poignant indication of pervasive social injustices that have yet to be adequately addressed. With the potential to produce broad economic and social benefits, the development of quality indigenous health systems warrants further analysis and practical strategies to improve current policies. Using the case of Mexico, home to the second-largest population of indigenous language speakers in the Americas, this paper examines the important—and often misunderstood—role of language in health care. From a historical perspective, Mexico’s policies and indigenous health initiatives indicate a movement toward progress, yet they seemingly fail to take into account the critical role of language—not only as a means of receiving health information—but as a means of communicating complex feelings and emotions and connecting with cultural conceptions of health. By understanding the important relationship between health and language, as well as the potential for language to serve as a resource and a protective factor for health, greater attention may be given to the development of participatory, culturally relevant, holistic care. To this end, this paper suggests that the field of language planning, with a long history of examining the multifaceted goals, approaches, and strategies to language policy and planning, could provide a significant contribution and help reduce existing disparities in indigenous health systems

    How Much is Learning Measurement Worth? Assessment Costs in Low-Income Countries

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    Timely and credible data on student learning has become a global issue in the ongoing effort to improve educational outcomes. With the potential to serve as a powerful diagnostic tool to gauge the overall health and well-being of an educational system, educational assessments have received increasing attention among specialists and the media. Though the stakes are high, relatively little is known about the cost-benefit ratio of various assessments compared to other educational expenditures. This paper presents an overview of four major types of assessments — national, regional, international and hybrid — and the costs that each has incurred within 13 distinct contexts, especially in low-income countries. The findings highlight broad variation in the total cost of assessment and the cost-per-learner. This underscores the importance of implementation strategies that appropriately consider scale, timeliness, and cost-efficiency as critical considerations for any assessment

    Learning First: A Research Agenda for Improving Learning in Low-Income Countries

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    In 2011, the Center for Universal Education (CUE) at the Brookings Institution spearheaded the development of a common policy agenda on global education entitled A Global Compact on Learning: Taking Action on Education in Developing Countries. The report recommended a call to action for a diverse group of international stakeholders to come together to work toward achieving quality education for all. As a part of this larger policy agenda, CUE works with various scholars and organizations to address the many issues within the scope of the Global Compact on Learning

    The role of nurse specialists in the delivery of integrated diabetes care: a cross-sectional survey of diabetes nurse specialist services

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    Objectives: International evidence suggests the diabetes nurse specialist (DNS) has a key role in supporting integrated management of diabetes. We examine whether hospital and community DNS currently support the integration of care, examine regional variation in aspects of the service relevant to the delivery of integrated care and identify barriers to service delivery and areas for improvement. Design: A cross-sectional survey of hospital and community-based DNS in Ireland. Methods: Between September 2015 and April 2016, a 67-item online survey, comprising closed and open questions on their clinical role, diabetes clinics, multidisciplinary working, and barriers and facilitators to service delivery, was administered to all eligible DNS (n=152) in Ireland. DNS were excluded if they were retired or on maternity leave or extended leave. Results: The response rate was 66.4% (n=101): 60.6% (n=74) and 89.3% (n=25) among hospital and community DNS, respectively. Most DNS had patients with stable (81.8%) and complicated type 2 diabetes mellitus (89.9%) attending their service. The majority were delivering nurse-led clinics (81.1%). Almost all DNS had a role liaising with (91%), and providing support and education to (95%), other professionals. However, only a third reported that there was local agreement on how their service should operate between the hospital and primary care. Barriers to service delivery that were experienced by DNS included deficits in the availability of specialist staff (allied health professionals, endocrinologists and DNS), insufficient space for clinics, structured education and issues with integration. Conclusions: Delivering integrated diabetes care through a nurse specialist-led approach requires that wider service issues, including regional disparities in access to specialist resources and formalising agreements and protocols on multidisciplinary working between settings, be explicitly addressed

    Mobiles for Literacy in Developing Countries: An Effectiveness Framework

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    In recent years, the advent of low-cost digital and mobile devices has led to a strong expansion of social interventions, including those that try to improve student learning and literacy outcomes. Many of these are focused on improving reading in low-income countries, and particularly among the most disadvantaged. Some of these early efforts have been called successful, but little credible evidence exists for those claims. Drawing on a robust sample of projects in the domain of mobiles for literacy, this article introduces a design solution framework that combines intervention purposes with devices, end users, and local contexts. In combination with a suggested set of purpose-driven methods for monitoring and evaluation, this new framework provides useful parameters for measuring effectiveness in the domain of mobiles for literacy

    In vitro dissolution models for the prediction of in vivo performance of an oral mesoporous silica formulation

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    Drug release from mesoporous silica systems has been widely investigated in vitro using USP Type II (paddle) dissolution apparatus. However, it is not clear if the observed enhanced in vitro dissolution can forecast drug bioavailability in vivo. In this study, the ability of different in vitro dissolution models to predict in vivo oral bioavailability in a pig model was examined. The fenofibrate-loaded mesoporous silica formulation was compared directly to a commercial reference product, Lipantil Supra®. Three in vitro dissolution methods were considered; USP Type II (paddle) apparatus, USP Type IV (flow-through cell) apparatus and a USP IV Transfer model (incorporating a SGF to FaSSIF-V2 media transfer). In silico modelling, using a physiologically based pharmacokinetic modelling and simulation software package (Gastroplus™), to generate in vitro/in vivo relationships was also investigated. The study demonstrates that the in vitro dissolution performance of a mesoporous silica formulation varies depending on the dissolution apparatus utilised and experimental design. The findings show that the USP IV transfer model was the best predictor of in vivo bioavailability. The USP Type II (paddle) apparatus was not effective at forecasting in vivo behaviour. This observation is likely due to hydrodynamic differences between the two apparatus and the ability of the transfer model to better simulate gastrointestinal transit. The transfer model is advantageous in forecasting in vivo behaviour for formulations which promote drug supersaturation and as a result are prone to precipitation to a more energetically favourable, less soluble form. The USP IV transfer model could prove useful in future mesoporous silica formulation development. In silico modelling has the potential to assist in this process. However, further investigation is required to overcome the limitations of the model for solubility enhancing formulations

    New multicellular marine macroalgae from the early Tonian of northwestern Canada

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    Molecular phylogenetic data suggest that photosynthetic eukaryotes first evolved in freshwater environments in the early Proterozoic and diversified into marine environments by the Tonian Period, but early algal evolution is poorly reflected in the fossil record. Here, we report newly discovered, millimeter- to centimeter-scale macrofossils from outershelf marine facies of the ca. 950–900 Ma (Re-Os minimum age constraint = 898 ± 68 Ma) Dolores Creek Formation in the Wernecke Mountains, northwestern Canada. These fossils, variably preserved by iron oxides and clay minerals, represent two size classes. The larger forms feature unbranching thalli with uniform cells, differentiated cell walls, longitudinal striations, and probable holdfasts, whereas the smaller specimens display branching but no other diagnostic features. While the smaller population remains unresolved phylogenetically and may represent cyanobacteria, we interpret the larger fossils as multicellular eukaryotic macroalgae with a plausible green algal affinity based on their large size and presence of rib-like wall ornamentation. Considered as such, the latter are among the few green algae and some of the largest macroscopic eukaryotes yet recognized in the early Neoproterozoic. Together with other Tonian fossils, the Dolores Creek fossils indicate that eukaryotic algae, including green algae, colonized marine environments by the early Neoproterozoic Era

    AACP Special Taskforce White Paper on Diversifying Our Investment in Human Capital

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    The 2015-2017 American Association of Colleges of Pharmacy (AACP) Special Taskforce on Diversifying our Investment in Human Capital was appointed for a two-year term, due to the rigors and complexities of its charges. This report serves as a white paper for academic pharmacy on diversifying our investment in human capital. The Taskforce developed and recommended a representation statement that was adapted and adopted by the AACP House of Delegates at the 2016 AACP Annual Meeting. In addition, the Taskforce developed a diversity statement for the Association that was adopted by the AACP Board of Directors in 2017. The Taskforce also provides recommendations to AACP and to academic pharmacy in this white paper
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